Academic Research

Artemis uses ultrashort pulses of extreme ultraviolet light to investigate ultrafast electron dynamics in condensed matter and gas-phase molecules, and for coherent lensless imaging.

The Beale group is interested in establishing structure-function relationships in functional materials, including catalytic solids and energy materials as a function of both time and space using both X-ray & optical spectroscopic and scattering method

Our group is interested in the structural and functional characterisation of membrane proteins that are involved in bacterial multidrug resistance and human diseases. We use protein X-ray crystallography for their structure determination.

We develop and use a variety of biophysical methods to characterise the interactions of biological macromolecules in solution and in the cell. These include proteins (soluble and membrane bound), protein/DNA complexes and nanoparticles.

We use a combination of X-ray crystallography, electron microscopy, biophysical methods and biochemistry to investigate how a variety of different enzymes achieve catalysis.

The Collaborative Computational Project for electron cryo-microscopy (CCP-EM) supports users and developers in biological EM. The three principal aims are:

CCP4 exists to produce and support a world-leading, integrated suite of programs that allows researchers to determine macromolecular structures by X-ray crystallography, and other biophysical techniques.

The Chaban Group is based at eBIC, Diamond Light Source.

In situ imaging of viral production in cells.

The Davies Group is based at eBIC, Diamond Light Source.

We are a spectroscopy research and applications development group.

Epigenetic modifications (reversible, heritable genetic changes that occur without changes in DNA sequence) lead to chromatin remodelling, altered gene expression and changes in the cellular phenotype.

Hough Group's research uses advanced structural biology and related methods to understand the structure and function of metalloproteins.

ISIS Neutron and Muon Source is the UK's national facility for materials research using neutrons and muons.

Led by Professor Peter Lee and Drs Alex Leung and Claire Walsh, the Materials, Structure and Manufacturing at Harwell (MSM@H) Group is a multidisciplinary group with over 30 members.

The Membrane Protein Laboratory (MPL) is a Diamond Light Source user facility based at Research Complex.  Re-funded by Wellcome until 2027, the MPL is a research and training resource for scientists interested understanding the structure and function of membrane proteins.&n

Our overarching goal is to develop new materials for sustainable energy applications via molecular engineering. This expressly notions product design at the molecular scale, embracing rational molecular design concepts to tailor a material to meet a specific need in device technology.

Octopus is a unique user facility with a suite of advanced laser-based imaging and laser trapping capabilities, such as super-resolution microscopy (including at cryogenic temperature), multidimensional single molecule imaging and tracking, confocal microscopy, light microscopy, an

The Orville group uses both synchrotron and X-ray free electron laser (XFEL) sources for serial MX strategies that exploit microcrystal slurries.

The Oxford MBE Group @ Harwell focuses on the growth of topological quantum materials, such as topological insulators, Weyl and Dirac semimetals, as well as topological magnetic systems, such as skyrmion, antiskyrmion, and chiral bobber materials using molecular beam

Parker Group work with a range of biological and non-biological systems including coccolithophores, bacteria and nanoplastics, using the microscopy and microbiology facilities at the Research Complex at Harwell to compliment their synchrotron-based research they under

The Perry Group studies the properties of functional materials, in particular metal oxides and chalcogenides. These materials host a diverse array of properties, such as ferroelectricity, superconductivity, magnetism, and exotic metallic behaviour.

The Rosalind Franklin Institute, led by Director Professor James Naismith, is the UK’s institute for technology development in life science.

The Schroeder Group seeks to revolutionise the development and supply of functional high-value chemical and pharmaceutical solid products by delivering a rapid innovation pipeline to integrated continuous manufacturing processes.

Research in the Spagnolo group focusses on the structural studies of macromolecular machines involved in gene replication, expression and

Ultra combines laser, detector and sample manipulation technology to probe ultrafast molecular dynamics to facilitate innovative research in the physical and life sciences in academia and industry.

Our research is using a targeted structural and functional approach to understanding at the molecular level how bacteria cause disease.

Our research aims to develop greater understanding of reactions occurring at material interfaces that underpin many sustainable technologies.

The XChem Lab at Research Complex is an extension of the XChem initiative, a joint lab spanning Diamond and CMD-Oxford, which developed and runs Diamond’s very successful XChem facility for crystal-based fragment screening.

Our research is aimed at an integrated, atomistic understanding of molecular mechanisms of large protein complexes and assemblies by developing and combining novel technologies for high-resolution cryoEM and cryo-electron tomography with complementary computati