Cellular and Molecular Biology

The Ng Group employs integrative structural, functional, and computational methodologies to provide a comprehensive understanding of viral glycoprotein architecture and functionality.

Our research consists of three major areas:

The Nucleic Acid Therapy Accelerator (NATA) is a newly established, independent, not-for-profit Medical Research Council (MRC) Unit – part of UK Research and Innovation (UKRI). Our mission is to advance the development of nucleic acid therapies an

OutFox Bio is a delivery technology company focused on the development and optimisation of next-generation lipid nanoparticle (LNP) gene delivery technologies to enable and expand the scope of gene therapy.

The Rosalind Franklin Institute, led by Director Professor James Naismith, is the UK’s institute for technology development in life science.

Research in the Spagnolo group focusses on the structural studies of macromolecular machines involved in gene replication, expression and

Wagner Group exploits the long-wavelength macromolecular crystallography beamline I23 at Diamond Light Source.

Our research is using a targeted structural and functional approach to understanding at the molecular level how bacteria cause disease.

The XChem Lab at Research Complex is an extension of the XChem initiative, a joint lab spanning Diamond and CMD-Oxford, which developed and runs Diamond’s very successful XChem facility for crystal-based fragment screening.

Our research is aimed at an integrated, atomistic understanding of molecular mechanisms of large protein complexes and assemblies by developing and combining novel technologies for high-resolution cryoEM and cryo-electron tomography with complementary computati