Cellular and Molecular Biology

We host a number of Diamond groups, including the Membrane Protein Laboratory and XChem. In addition, we support the MRC funded Nucleic Acid Therapy Accelerator, Rosalind Franklin Institute, CCP4 and groups within the pharmaceutical industry

Cellular and Molecular Biology
Peter at work

Membrane Protein Laboratory (MPL)

The Membrane Protein Laboratory (MPL) is a Diamond Light Source user facility based at Research Complex.  Re-funded by Wellcome until 2027, the MPL is a research and training resource for scientists interested understanding the structure and function of membrane proteins.&n

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NanoVation Therapeutics UK

NanoVation Therapeutics (NTx) is a delivery technology company focused on the development and optimisation of next-generation lipid nanoparticle (LNP) gene delivery technologies to enable and expande the scope of gene therapy.

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Ng Research Overview

Ng Group at Diamond

The Ng Group employs integrative structural, functional, and computational methodologies to provide a comprehensive understanding of viral glycoprotein architecture and functionality.

Our research consists of three major areas:

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Group

Nucleic Acid Therapy Accelerator (NATA)

The Nucleic Acid Therapy Accelerator (NATA) is a newly established, independent, not-for-profit Medical Research Council (MRC) Unit – part of UK Research and Innovation (UKRI). Our mission is to advance the development of nucleic acid therapies an

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RFI handover

Rosalind Franklin Institute

The Rosalind Franklin Institute, led by Director Professor James Naismith, is the UK’s institute for technology development in life science.

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Spagnolo Group overview

Spagnolo Group

Research in the Spagnolo group focusses on the structural studies of macromolecular machines involved in gene replication, expression and

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Wagner Group photo

Wagner Group at Diamond

Wagner Group exploits the long-wavelength macromolecular crystallography beamline I23 at Diamond Light Source.

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Walsh Group overall picture

Walsh Group at Diamond

Our research is using a targeted structural and functional approach to understanding at the molecular level how bacteria cause disease.

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XChem overall picture

XChem at Diamond

The XChem Lab at Research Complex is an extension of the XChem initiative, a joint lab spanning Diamond and CMD-Oxford, which developed and runs Diamond’s very successful XChem facility for crystal-based fragment screening.

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eBIC group photo

Zhang Group at Diamond

Our research is aimed at an integrated, atomistic understanding of molecular mechanisms of large protein complexes and assemblies by developing and combining novel technologies for high-resolution cryoEM and cryo-electron tomography with complementary computati

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