Chloe Seddon

Chloe obtained her Integrated Masters (MBio) in Biochemistry at the University of Warwick. Her PhD focuses on bacterial conjugation, the transfer of single-stranded DNA from a donor cell to a recipient cell in proximity. More specifically, she works on conjugation in Klebsiella pneumoniae, a clinically concerning pathogen that causes hospital-acquired pneumonia and uses conjugation to disseminate antibiotic resistance genes. Conjugation utilises the type IV secretion system, through which outer membrane proteins have a role in mediating efficient DNA transfer. Chloe works on the outer membrane proteins of this system which confer stabilisation during conjugation and those that prevent redundant conjugation from occurring.