Chloe obtained her BA and Integrated Masters (MBio) degrees in biochemistry at the University of Warwick. Her PhD focuses on bacterial conjugation, the transfer of single-stranded DNA from a donor cell to a recipient cell in proximity. More specifically, she works on conjugation in Klebsiella pneumoniae, a clinically concerning pathogen that causes hospital-acquired pneumonia and uses conjugation to disseminate antibiotic resistance genes. Conjugation utilises the type IV secretion system, through which outer membrane proteins have a role in mediating efficient DNA transfer. Chloe works on the outer membrane proteins of this system which confer stabilisation during conjugation and those that prevent redundant conjugation from occurring.
Imperial College London