Cellular and Molecular Biology

The Membrane Protein Laboratory (MPL) is a Wellcome Trust funded user facility and the XChem Laboratory developing methodology in computational and synthetic chemistry for Diamond Light Source. More recently, the Medical Research Council (MRC) funded Nucleic Acid Therapy Accelerator (NATA).

Related Events

Science Up Close

Harwell Open Day

29/06/2024
10:00 - 16:00
Rutherford Appleton Laboratory

We're excited to open our doors for Harwell Open Day this year on 29th June. Members of the public are invited to explore Research Complex, alongside Diamond Light Source, ISIS, the Central Laser Facility, RAL Space, and more!

Read more

Related News

Related Research Groups

Arctoris

Arctoris is a biotech services company based in Oxford, Singapore and Boston that applies laboratory automation and computational approaches to accel

Read more

Beis Group

Our group is interested in the structural and functional characterisation of membrane proteins that are involved in bacterial multidrug resistance and human diseases. We use protein X-ray crystallography for their structure determination.

Read more
BM Group overall picture

Biophysical Methods Group

We develop and use a variety of biophysical methods to characterise the interactions of biological macromolecules in solution and in the cell. These include proteins (soluble and membrane bound), protein/DNA complexes and nanoparticles.

Read more

Carr Group

We use a combination of X-ray crystallography, electron microscopy, biophysical methods and biochemistry to investigate how a variety of different enzymes achieve catalysis.

Read more

Etcembly

Etcembly, based in the Atlas Centre at Harwell Campus is a Generative AI (artificial intelligence) T Cell Receptor (TCR) discovery engineering company.

Read more
Flaig Group

Flaig Group at Diamond

Epigenetic modifications (reversible, heritable genetic changes that occur without changes in DNA sequence) lead to chromatin remodelling, altered gene expression and changes in the cellular phenotype.

Read more
Hough Group

Hough Group at Diamond

Hough Group's research uses advanced structural biology and related methods to understand the structure and function of metalloproteins.

Read more
Peter at work

Membrane Protein Laboratory (MPL)

The Membrane Protein Laboratory (MPL) is a Diamond Light Source user facility based at Research Complex.  Re-funded by Wellcome until 2027, the MPL is a research and training resource for scientists interested understanding the structure and function of membrane proteins.&n

Read more

NanoVation Therapeutics UK

NanoVation Therapeutics (NTx) is a delivery technology company focused on the development and optimisation of next-generation lipid nanoparticle (LNP) gene delivery technologies to enable and expande the scope of gene therapy.

Read more
Ng Research Overview

Ng Group at Diamond

The Ng Group employs integrative structural, functional, and computational methodologies to provide a comprehensive understanding of viral glycoprotein architecture and functionality.

Our research consists of three major areas:

Read more
Group

Nucleic Acid Therapy Accelerator (NATA)

The Nucleic Acid Therapy Accelerator (NATA) is a newly established, independent, not-for-profit Medical Research Council (MRC) Unit – part of UK Research and Innovation (UKRI). Our mission is to advance the development of nucleic acid therapies an

Read more
RFI handover

Rosalind Franklin Institute

The Rosalind Franklin Institute, led by Director Professor James Naismith, is the UK’s institute for technology development in life science.

Read more
Spagnolo Group overview

Spagnolo Group

Research in the Spagnolo group focusses on the structural studies of macromolecular machines involved in gene replication, expression and

Read more
Wagner Group photo

Wagner Group at Diamond

Wagner Group exploits the long-wavelength macromolecular crystallography beamline I23 at Diamond Light Source.

Read more
Walsh Group overall picture

Walsh Group at Diamond

Our research is using a targeted structural and functional approach to understanding at the molecular level how bacteria cause disease.

Read more
XChem overall picture

XChem at Diamond

The XChem Lab at Research Complex is an extension of the XChem initiative, a joint lab spanning Diamond and CMD-Oxford, which developed and runs Diamond’s very successful XChem facility for crystal-based fragment screening.

Read more
eBIC group photo

Zhang Group at Diamond

Our research is aimed at an integrated, atomistic understanding of molecular mechanisms of large protein complexes and assemblies by developing and combining novel technologies for high-resolution cryoEM and cryo-electron tomography with complementary computati

Read more

Related Equipments

Mosquito Crystal

The mosquito crystal helps scientists to automate and streamline liquid handling workflows in protein crystallography drop setting and be

Read more