Research Showcase

RCaH continues to deliver outstanding and impactful science of international quality.

Here are some recent research highlights.

CLF collaborative study highlights flaws in breast cancer drug

A consortium of scientists from across the UK, including four at the Central Laser Facility (CLF), have used the OCTOPUS imaging facility at the CLF to prove that a well-established breast cancer drug paradoxically boosts the growth of tumour cells in vitro. A new study published in eLife, has shown that the breast cancer drug lapatinib can sometimes…

Diamond Light Source particle accelerator ‘freezes time’ to reveal 3D printing secrets

Researchers have used a particle accelerator to ‘freeze time’ during 3D printing, studying a process over milliseconds to help improve safety-critical components. Led by Professor Peter Lee, the team used an X-ray beamline at the Diamond Light Source to analyse the rapid surface-level changes that take place during laser additive manufacturing (LAM). The LAM process…

Mapping the complete reaction path of a complex photochemical reaction

Using the Artemis laser, a team from University of Southampton in collaboration with scientists at the CLF have been working to try to uncover what really happens during these extremely fast timescales. To date, observing complex photochemical reactions has hitherto offered an incomplete picture, because most spectroscopic techniques are not able to measure key parts…

Illuminating the mechanism of photoactivation of a prototypical fluorescent protein

Using time-resolved infrared spectroscopy, scientists have unravelled with great accuracy the extremely fast structure changes that occur in a photochromic fluorescent protein as it switches from its dark (off) to light (on) state.