Research Showcase

RCaH continues to deliver outstanding and impactful science of international quality.

Here are some recent research highlights.

Research reveals how bacteria hijacks proteins to transport antibacterial peptides

Bacterial species are under continuous warfare with each other for access to nutrients. To gain an advantage in this struggle, they produce antibacterial compounds that target and kill closely related species. Now, researchers led by the Research Complex’s Dr. Konstantinos Beis from Imperial College London, together with Professor Jonathan Heddle from Jagiellonian University, Krakow, have…

Research Complex, Rosalind Franklin, Diamond Light Source and Oxford University collaborate on high-res imaging which reveals organisational behaviour of chlamydia-causing bacteria

A powerful new imaging technique has helped researchers at Research Complex at Harwell, the Rosalind Franklin Institute, Diamond Light Source and Oxford University shed light on an important class of bacteria responsible for a range of diseases in humans and animals. Best known as the cause of a sexually transmitted infection, Chlamydiae are a diverse…

Research Showcase - Commercialised Gold Catalyst

Active site in the commercialised gold catalyst identified

This study brought together advanced spectroscopy (EXAFS), microscopy, theory and catalyst synthesis to solve a key problem. The use of gold as a catalyst for acetylene hydrochlorination has been known for more than 30 years. However, previous ex situ studies created nanoparticles that clouded the scientific picture of what was really occurring. In situ studies…

ULTRA study could facilitate large-scale screening tests of drugs using 2D-IR spectroscopy

A team of scientists from the University of Strathclyde have used the CLF’s Lifetime laser to retrieve sequence-specific information about DNA-ligand binding. ​Their results provide promising evidence for the potential of using 2D-IR alongside ANOVA-PCA as a rapid and effective probe of DNA binding interactions. The molecular interactions between proteins and DNA are essential for biological function, which is why they…