Research Showcase

RCaH continues to deliver outstanding and impactful science of international quality.

Here are some recent research highlights.

Research Showcase - Commercialised Gold Catalyst

Active site in the commercialised gold catalyst identified

This study brought together advanced spectroscopy (EXAFS), microscopy, theory and catalyst synthesis to solve a key problem. The use of gold as a catalyst for acetylene hydrochlorination has been known for more than 30 years. However, previous ex situ studies created nanoparticles that clouded the scientific picture of what was really occurring. In situ studies…

ULTRA study could facilitate large-scale screening tests of drugs using 2D-IR spectroscopy

A team of scientists from the University of Strathclyde have used the CLF’s Lifetime laser to retrieve sequence-specific information about DNA-ligand binding. ​Their results provide promising evidence for the potential of using 2D-IR alongside ANOVA-PCA as a rapid and effective probe of DNA binding interactions. The molecular interactions between proteins and DNA are essential for biological function, which is why they…

CLF collaborative study highlights flaws in breast cancer drug

A consortium of scientists from across the UK, including four at the Central Laser Facility (CLF), have used the OCTOPUS imaging facility at the CLF to prove that a well-established breast cancer drug paradoxically boosts the growth of tumour cells in vitro. A new study published in eLife, has shown that the breast cancer drug lapatinib can sometimes…

Diamond Light Source particle accelerator ‘freezes time’ to reveal 3D printing secrets

Researchers have used a particle accelerator to ‘freeze time’ during 3D printing, studying a process over milliseconds to help improve safety-critical components. Led by Professor Peter Lee, the team used an X-ray beamline at the Diamond Light Source to analyse the rapid surface-level changes that take place during laser additive manufacturing (LAM). The LAM process…