Professor Laura Spagnolo is set to expand her group at Research Complex, having won a new grant from the Biotechnology and Biological Sciences Research Council (BBSRC) to explore the RNA-binding protein Staufen1.
Since its discovery, Staufen1 has been studied for its involvement in a diverse set of aspects of RNA metabolism, ranging from RNA localisation to decay. Given its pivotal role in cellular RNA metabolism, several studies have explored the mechanistic impact of Staufen1 in a wide variety of cell functions ranging from cell growth to cell death, as well as in various disease states.
Laura explains:
‘This project aims to identify the molecular mechanism governing the functions of the Staufen1 protein, using our unique expertise in the structural and quantitative biology of protein:nucleic acid complexes, our track record on Staufen1 structural biochemistry, and access to beyond-state-of-the-art technology at Glasgow, Research Complex at Harwell and the Central Laser Facility.’
Research Complex Director John Hand says:
‘Congratulations to Professor Spagnolo for securing this prestigious grant. The project promises to strengthen our cross-collaboration with the University of Glasgow, and makes excellent use of our expertise at Research Complex in structural biology, cryo-ET and more.’
Applications are now open for two roles, a Research Associate, and Research Assistant. The closing date is 12th August.