RCaH Seminars will be held on the 2nd Thursday of each month from
1400 – 1500 hrs in the seminar rooms.
Please note: First seminar will be held on Friday 10 September
Change of speaker for 10 September - Tina Iverson is no longer available.
| Date | Speaker(s) | Organisation | Topic |
| 2010 | |||
| 10 Sept | Guiliano Siligardy | Diamond Light Source | B23 CD beamline: Applications to Life Sciences |
| Abstract Circular dichroism (CD) is the spectroscopic technique of choice to characterise chiral molecules such as peptides, proteins, nucleic acids (DNA and RNA), carbohydrates, lipids and small organic molecules (drugs). Although a low resolution technique compared to that of X-ray crystallography and NMR, CD is the technique of choice for systems that do not crystallise or are largely flexible like natively disordered proteins that constitute a significant proportion of proteins. Ligand binding by CD not only provides the stoichiometry and the binding affinity but reveals also whether there are conformational changes induced by the molecular interactions much faster than any other technique. The combined high photon flux and micro beam make Diamond B23 beamline uniquely suited for CD measurements in micro-devices. Developments in this area together with ligand binding interaction studies of a variety of systems will be discussed |
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| 14 Oct | Ilan Davis | Oxford University | Tbc |
| 11 Nov | Peter Parker | KCL | Tbc |
| 9 Dec | John McGeehan | University of Portsmouth | Tbc |
| 2011 | |||
| 13 Jan | Prof Francis Barr | University of Liverpool CR-UK Cancer Research Centre |
Tbc |
| 10 Feb | Jim Naismith | St Andrews | Tbc |