Isothermal Titration Calorimetry

Applications include:

  • Characterization of molecular interactions of small molecules, proteins, antibodies, nucleic acids, lipids and other biomolecules, including binding affinities, entropies and enthalpies, and stochiometry.
  • Lead optimization.
  • Characterization of mechanism of action
  • Enzyme kinetics.
  • Assessment of the effect of molecular structure changes on binding mechanisms.
  • Assessment of biological activity.

For more information please go to the GE website:
http://www.microcal.com/products/itc/itc200.asp