2011 Publications

Degenerate RNA Packaging Signals in the Genome of Satellite Tobacco Necrosis Virus: Implications for the Assembly of a T=1 Capsid
David H J Bunka, Stephen W Lane, Claire L Lane, Eric C Dykeman, Robert J Ford, Amy M Barker, Reidun Twarock, Simon E V Phillips, Peter G Stockley
J Mol Biol, Volume 413, Pages 51-65

Construction and Crystal Structure of Recombinant STNV Capsids
Stephen W Lane, Caitriona A Dennis, Claire L Lane, Chi H Trinh, Pierre J Rizkallah, Peter G Stockley, Simon E V Phillips
J Mol Biol, Volume 413, Pages 41-50 

XtalPiMS: A PiMS-based web application for the management and monitoring of crystallization trials
Ed Daniel, Bill Lin, Jonathan M Diprose, Susanne L Griffiths, Chris Morris, Ian M Berry, Raymond J Owens, Richard Blake, Keith S Wilson, David I Stuart, Robert M Esnouf
J Struct Biol, Volume 175, Pages 230 - 235

Expression of protein complexes using multiple Escherichia coli protein co-expression systems: A benchmarking study
Didier Busso, Yoav Peleg, Tatjana Heidebrecht, Christophe Romier, Yossi Jacobovitch, Ada Dantes, Loubna Salim, Edouard Troesch, Anja Schuetz, Udo Heinemann, Gert Folkers, Arie Geerlof, Matthias Wilmanns, Andrea Polewacz, Claudia Quedenau, Konrad Bussow, Rachel Adamson, Elena Blagova, Julia Walton, Jared Cartwright, Louise Bird, Ray Owens, Nick Berrow, Keith Wilson, Joel Sussman, Anastassis Perrakis, Patrick Celie
Link: J Struct Biol, Volume 175, Pages 159 - 170

Recording information on protein complexes in an information management system
Marc Savitsky, Jon Diprose, Chris Morris, Susanne L Griffiths, Edward Daniel, Bill Lin, Susan Daenke, Benjamin Bishop, Christian Siebold, Keith Wilson, Richard Blake, David Stuart, Robert Esnouf
Link: J Struct Biol, Volume 175, Pages 224 - 229

A Comparative Picosecond Transient Infrared Study of 1-Methylcytosine and 5'-dCMP That Sheds Further Light on the Excited States of Cytosine Derivatives
Paraic Keane, Michal Wojdyla, Gerard Doorley, Graeme Watson, Ian Clark, Gregory Greetham, Anthony Parker, Michael Towrie, John Kelly, Susan Quinn
Link: J Am Chem Soc, Volume 133, Pages 4212 - 4215

The role of CN and CO ligands in the vibrational relaxation dynamics of model compunds of the [FeFe]-hydrogenase enzyme
Spyridon Kaziannis, Joseph Wright, Marco Candelaresi, Rafal Kania, Gregory Greetham, Anthony Parker, Christopher Pickett, Neil Hunt
Link: Phys Chem Chem Phys, Volume 13, Pages 10295 - 10305

Relationship between protein structural fluctuations and rebinding dynamics in ferric haem nitrosyls
Neil Hunt, Gregory Greetham, Michael Towrie, Anthony Parker, Nicholas Tucker
Link: Biochem, Volume 433, Pages 459 - 468

Structure of the human histamine H(1) receptor in complex with doxepin
Tatsuro Shimamura, Mitsunori Shiroishi, Simone Weyand, Hirokazu Tsujimoto, Graeme Winter, Vsevolod Katritch, Ruben Abagyan, Vadim Cherezov, Wei Liu, Gye Won Han, Takuya Kobayashi, Raymond C Stevens, So Iwata
Link: Nature, Volume 475, Pages 65 - 70

Single Domain Intracellular Antibodies from Diverse Libraries Emphasizing Dual Function of LM02 Protein Interactions Using a Single VH Domain
Tomoyuki Tanaka, Helen Sewell, Simon Waters, Simon E V Phillips, Terence H Rabbitts
Link: J Biol Chem, Volume 286 Pages 3707-3716

Tyrosine 381 in E coli copper amine oxidase influences substrate specificity
Christian R P Kurtis, Peter F Knowles, Mark R Parsons, Thembaninkosi G Gaule, Simon E V Phillips, Michasel J McPherson
Link: J Neural Transm, Volume 118 Pages 1043 - 1053

Conformational changes in IgE contribute to its uniquely slow dissociation rate from receptor FcεRI
Mary D Holdom, Anna M Davies, Joanne E Nettleship, Sarah C Bagby, Balvinder Dhaliwal, Enrico Girardi, James Hunt, Hannah J Gould, Andrew J Beavil, James M McDonnell, Ray J Owens, Brian J Sutton
Link: Nature & Structural Biology, Volume 18 Pages 571-576. Can also be found here.

Human-EGFR displays high-affinity EGF-binding and the asymmetry of the Drosophilia-EGFR via interactions with the plasma membrane
Christopher J. Tynan, Selene K. Roberts, Daniel J. Rolfe, David T. Clarke, Hannes H. Loeffler, Johannes Kästner, Martyn D. Winn, Peter J. Parker and Marisa L. Martin-Fernandez
Link: Molecular and Cellular Biology, June 2011, Vol. 31, No. 11, p. 2241-2252

The Protein Information Management System (PiMS): a generic tool for any structural biology research laboratory
Chris Morris, Anne Pajon, Susanne L Griffiths, Ed Daniel, Marc Savitsky, Bill Lin, Jonathan M Diprose, Alan Wilter da Silva, Katya Pilicheva, Peter Troshin, Johannes van Niekerk, Neil Isaacs, James Naismith, Colin Nave, Richard Blake, Keith S Wilson, David I Stuart, Kim Henrick, Robert M Esnouf
Link: Acta Crystallographica Section D: Biological Crystallography, Volume D67 Pages 249-260

Macromolecular complexes in crystals and solutions
Evgeny Krissinel
Link: Acta Crystallographica Section D: Biological Crystallography, Volume D67 Pages 376-385

Evaluating the solution from MrBUMP and BALBES
Ronan M Keegan, Fei Long, Vincent J Fazio, Martyn D Winn, Garib N Murshudov, Alexi A Vagin
Link: Acta Crystallographica Section D: Biological Crystallography, Volume D67 Pages 313-323

Overview of the CCP4 suite and current developments
Martyn D Winn, Charles C Ballard, Kevin D Cowtan, Eleanor J Dodson, Paul Emsley, Phill R Evans, Ronan M Keegan, Eugene B Krissinel, Andrew G W Leslie, Airlie McCoy, Stuart J McNicholas, Garib N Murshudov, Navraj S Pannu, Elizabeth A Potterton, Harold R Powell, Randy J Read, Alexei Vagin, Keith S Wilson
Link: Acta Crystallographica Section D: Biological Crystallography, Volume D67 Pages 235-242

Vibrationally Quantum-State-Specific Reaction Dynamics of H Atom Abstraction by CN Radical in Solution
Stuart J Greaves, Rebecca A Rose, Thomas A A Oliver, David R Glowacki, Michael N Ashfold, Jeremy N Harvey, Ian P Clark, Gregory M Greetham, Anthony W Parker, Michael Towrie, Andrew J Orr-Ewing
Link: Science, Vol 331, Pages 1423 - 1426

Crystal Structures of Penicillin-Binding Protein 3 from Pseudomonas aeruginosa: Comparison of Native and Antibiotic Bound Forms
Sainsbury S, Bird L, Rao V, Shepherd SM, Stuart DI, Hunter WN, Owens RJ, Ren J
Link: Journal of Molecular Biology, Vol 405, Issue 1, 7 January 2011, Pages 173-184

A paper showing how two important antibiotics bind to their target protein.
To read more click here.

The structure of New Delhi metallo-ß-lactamase 1 (NDM-1)
Victoria L Green, Anil Verma, Raymond J Owens, Simon E V Phillips, Stephen B Carr
Acta Cryst F, Volume 67

Crystal structure of a bacterial homolgue of the bile acid sodium symporter ASBT
Nien-Jen Hu, So Iwata, Alexander D Cameron, David Drew
Nature, Volume 478

Time-Resolved Resonance Raman Spectroscopy: Exploring Reactive Intermediates
Sangram Keshari Sahoo, Siva Umapathy, Anthony W Parker
Applied Spectroscopy, Volume 65/10, Pages 1087 - 1115

High throughput construction and small scale expression screening of multi-tag vectors in Escherichia coli
Louise E Bird
Methods, Volume 55, Pages 29 - 37

Codanin-1 mutations in congenital dyserythropoietic anemia type 1 affect HP1A localization in erythroblasts
R Renella, N A Roberts, J M Brown, M De Gobbi, L E Bird, T Hassanali, J A Sharpe, J Sloane-Stanley, D J Ferguson, J Cordell, V J Buckle, D R Higgs, W G Wood
Blood, Volume 117, Pages 6928-38

Codanin-1 mutations in congenital dyserythropoietic anemia type 1 affect HP1Α localization in erythroblasts
R Renella, N A Roberts, J M Brown, M De Gobbi, L E Bird, T Hassanali, J A Sharpe, J Sloane-Stanley, D J Ferguson, J Cordell, V J Buckle, D R Higgs, W G Wood
Blood, Volume 117, Pages 6928-38

Laser Acceleration of Electrons, Protons, and Ions and Medical Applications of Laser-Generated Secondary Sources of Radiation and Particles
Borghesi M et al
Proceedings of SPIE-The International Society for Optical Engineering

Emerging Raman Techniques for Rapid Noninvasive characterization of Pharmaceutical Samples and Containers
P Matousek
Spectroscopy, Volume 26, Pages 44 - 51

Dependence of signal on depth in transmission raman spectroscopy
P Matousek, N Everall, D Littlejohn, A Nordon, M Bloomfield
Applied Spectroscopy, Volume 65, Pages 724 -733

Automated multidimensional single molecule fluorescence microscopy feature detection and tracking
D Rolfe, et al
Eur Biophys J

Fluorescent gallium and indium bis(thiosemicarbazonates) and their radiolabelled analogues: Synthesis, structures and cellular confocal fluorescence imaging investigations
R L Arrowsmith, et al
Daltan Transactions, Volume 40, Pages 6238-6252

Phototriggering electron flow through Re(I)- modified Pseudomonas aeruginosa Azurins
A M Blanco-Rodriguez, et al
Chemistry a European J, Volume 17, Pages 5349-5360

Photoinduced intramolecular Tryptophan Oxidation and excited-state behaviour of Re(L-AA)(CO)(3)(alpha-diimine)(+)(L=Pyridine or Imidazole, AA - Tryptophan, yrosine, Phenylalanine)
A M Blanco-Rodriguez, M Towrie, J Sykora, S Zalis, A Vlcek
Inorganic Chemistry, Volume 50, Pages 6122-6134

Development of fluorophore dynamics imaging as a probe for lipid domains in model vesicles and cell membranes
S W Botchway, A M Lewis, C D Stubbs
Eur Biophys J with Biophysics Lets, Volume 40, Pages 131-141

Recent advances in the application of transmission Raman spectroscopy to pharmaceutical analysis
K Buckley, P Matousek
J Pharm & Biomed Analysis, Volume 55, Pages 645-652

A multi-laser facility for combined single molecule and ensemble microscopy
D T Clarke, et al
Rev Sci Inst

Circular dichroism and its use in protein-folding studies
D T Clarke
Methods in mol biol, Volume 752, Pages 59 - 72

Photochemistry of (eta(6)-Arene)CR(CO)(3) (Arene=Methylbenzoate, Naphthalene, or Phenanthrene) in n-Heptane Solution: Population of Two Excited States Following 400 nm Excitation as detected by Picosecond Time-Resolved Infrared Spectroscopy
I P Clark, et al
J Phys Chem, Volume 115, Pages 2985 - 2993

Ultrafast Excited-State Dynamics of Rhenium(I) Photosensitizers Re(CI0(CO)(3)(N,N) and Re(imidazole)(CO)(3)(N,N) (_): Diimine Effects
A El Nahhas, et
Inorg Chemistry, Volume 50, Pages 2932-2943

Combined experimental and theoretical investigation into C-H activation of cyclic alkanes by Cp 'Rh(CO)(2)(Cp'=eta(5)-C(5)H(5) or eta(5)-C(5)Me(5))
M W George et al
Daltan Transactions, Volume 40, Pages 1751-1757

Characterisation of transmission Rman spectroscopy for rapid quantitative analysis of intact multi-component pharmaceutical capsules
M D Hargreaves, et al
J Pharm & Biomed Analysis, Volume 54, Pages 463-468

CAR Modulates E-Cadherin Dynamics in the Presence of Adenovirus Type 5
F Hussain, et al
PLoS, Volume 6, Pages 8: 23056

Modulation of Contact Order Effects in the Two-State Folding of Stefins A and B
C Jelinska, et al
J Biophysics, Volume 100, Pages 2268-2274

REFMAC5 for the refinement of macromolecular crystal structures
G N Murshudov, P Skubak, A A Lebedev, N S Pannu, R A Steiner, R A Nicholls, M D Winn, F Long, A A Vagin
Acta Crystallographica, Volume 67, Pages 355-367

Surface enhanced spatially offset Raman spectroscopic (SESORS) imaging - the next dimension
N Stone, et al
Chemical Science, Volume 2, Pages 776-780

Subcellular and single-molecule imaging of plant fluorescentproteins using total internal reflection fluorescence microscopy (TIRFM)
G Vizcay-Barrena, et al
J Experimental Botany

Simultaneous, multi-colour single molecule imaging of the entire ErbB receptor family in live cells
S Webb, et al
Eur Biophysics J with Biophysics Letters, Volume 40, Pages 154

Nanofluidic networks created and controlled by light
D A Woods, C D Mellor, J M Taylor, C D Bain, A D Ward
Soft Matter, Volume 7, Pages 2517- 2520